Managing Microsoft Exchange Server environments can be complex — especially when trying to stay compliant with supported versions, OS builds, Active Directory, and client compatibility. That’s why this Exchange Server Supportability Matrix is your go-to guide.
Whether you’re upgrading to Exchange Server 2019 CU15, planning a migration to Exchange Server SE, or ensuring browser and .NET compatibility, this resource breaks down all the supported configurations in one place.
But understanding supportability is only the first step — keeping your environment secure and fully supported is an ongoing process. That’s where Medha Cloud Exchange Server Support comes in.
| Version | Build(s) |
|---|---|
| Exchange Server SE | RTM (not yet available) |
| Exchange Server 2019 | CU15 (2025H1), CU14 (2024H1) |
| Exchange Server 2016 | CU23 |
| Version | Operating Systems | Server Edition | Installation Options |
|---|---|---|---|
| Exchange Server SE | Windows Server 2025, 2022, 2019 | Datacenter, Standard | Desktop Experience, Server Core (recommended) |
| Exchange Server 2019 | Windows Server 2025, 2022, 2019 | Datacenter, Standard | Desktop Experience, Server Core (recommended) |
| Exchange Server 2016 | Windows Server 2016, 2012 R2, 2012 | Datacenter, Standard | Desktop Experience |
| Version | Operating Systems |
|---|---|
| Exchange Server SE Mgmt. Tools | Windows Server 2025, 2022, 2019, Windows 11, Windows 10 (64-bit) |
| Exchange Server 2019 Mgmt. Tools | Same as above |
| Exchange Server 2016 Mgmt. Tools | Windows Server 2016, 2012 R2, 2012, Windows 10 (64-bit) |
| Version | AD Servers | Forest Functional Levels |
|---|---|---|
| Exchange Server SE | Windows Server 2025, 2022, 2019, 2016, 2012 R2 | Windows Server 2016, 2012 R2 |
| Exchange Server 2019 | Same as above | Same as above |
| Exchange Server 2016 | Windows Server 2022, 2019, 2016, 2012 R2, 2012 | Windows Server 2016, 2012 R2, 2012 |
| Version | Browsers | S/MIME Support |
|---|---|---|
| Exchange Server SE OWA / EAC | Edge (Chromium & IE Mode), Firefox, Chrome, Safari | Yes, Yes, Yes, No, Yes, No |
| Exchange Server SE OWA Light | Edge, Safari | S/MIME not available |
| Exchange Server 2019 OWA / EAC | Edge (Chromium & IE Mode), Firefox, Chrome, Safari | Yes, Yes, Yes, No, Yes, No |
| Exchange Server 2019 OWA Light | Edge, Safari | S/MIME not available |
| Exchange Server 2016 OWA / EAC | Edge (Chromium & IE Mode), Firefox, Chrome, Safari | No, Yes, No, No, No, No |
| Exchange Server 2016 OWA Light | Edge, Firefox, Chrome, Safari | S/MIME not available |
| Version | Clients |
|---|---|
| Exchange Server SE | Microsoft 365 Apps, Outlook 2024/2021/2019/2016, Outlook for Mac, iOS, Android |
| Exchange Server 2019 | Same as above |
| Exchange Server 2016 | Same as above |
| Version | OS | .NET Framework |
|---|---|---|
| Exchange Server SE | Windows Server 2025/2022 | .NET Framework 4.8.1 (recommended) or 4.8 |
| Exchange Server 2019 CU15/CU14 | Windows Server 2025/2022 | .NET Framework 4.8.1 or 4.8 |
| Exchange Server 2019 CU15/CU14 | Windows Server 2019 | .NET Framework 4.8 |
| Exchange Server 2016 CU23 | All supported OS | .NET Framework 4.8 |
With deep expertise in Microsoft technologies, Medha Cloud offers proactive, end-to-end support for Exchange Server environments — from legacy systems to modern hybrid deployments. Our services include:
Whether you’re dealing with compatibility issues or planning to migrate to Microsoft 365, our team ensures your Exchange deployment is secure, scalable, and fully compliant.
➡️ Upgrade your Exchange Server with confidence using our managed services.
➡️ Migrate to Microsoft 365 with zero downtime and expert guidance.
For full support from certified Exchange professionals, visit:
👉 Medha Cloud Exchange Server Support
