Managing Microsoft Exchange Server environments can be complex — especially when trying to stay compliant with supported versions, OS builds, Active Directory, and client compatibility. That's why this Exchange Server Supportability Matrix is your go-to guide.

Whether you're upgrading to Exchange Server 2019 CU15, planning a migration to Exchange Server SE, or ensuring browser and .NET compatibility, this resource breaks down all the supported configurations in one place.

But understanding supportability is only the first step — keeping your environment secure and fully supported is an ongoing process. That's where Medha Cloud Exchange Server Support comes in.

Exchange Server Supportability Matrix

Supported Versions and Builds

Version	Build(s)
Exchange Server SE	RTM (not yet available)
Exchange Server 2019	CU15 (2025H1), CU14 (2024H1)
Exchange Server 2016	CU23

Supported Operating Systems

Version	Operating Systems	Server Edition	Installation Options
Exchange Server SE	Windows Server 2025, 2022, 2019	Datacenter, Standard	Desktop Experience, Server Core (recommended)
Exchange Server 2019	Windows Server 2025, 2022, 2019	Datacenter, Standard	Desktop Experience, Server Core (recommended)
Exchange Server 2016	Windows Server 2016, 2012 R2, 2012	Datacenter, Standard	Desktop Experience

Management Tools Compatibility

Version	Operating Systems
Exchange Server SE Mgmt. Tools	Windows Server 2025, 2022, 2019, Windows 11, Windows 10 (64-bit)
Exchange Server 2019 Mgmt. Tools	Same as above
Exchange Server 2016 Mgmt. Tools	Windows Server 2016, 2012 R2, 2012, Windows 10 (64-bit)

Supported Active Directory Environments

Version	AD Servers	Forest Functional Levels
Exchange Server SE	Windows Server 2025, 2022, 2019, 2016, 2012 R2	Windows Server 2016, 2012 R2
Exchange Server 2019	Same as above	Same as above
Exchange Server 2016	Windows Server 2022, 2019, 2016, 2012 R2, 2012	Windows Server 2016, 2012 R2, 2012

Supported Browsers

Version	Browsers	S/MIME Support
Exchange Server SE OWA / EAC	Edge (Chromium & IE Mode), Firefox, Chrome, Safari	Yes, Yes, Yes, No, Yes, No
Exchange Server SE OWA Light	Edge, Safari	S/MIME not available
Exchange Server 2019 OWA / EAC	Edge (Chromium & IE Mode), Firefox, Chrome, Safari	Yes, Yes, Yes, No, Yes, No
Exchange Server 2019 OWA Light	Edge, Safari	S/MIME not available
Exchange Server 2016 OWA / EAC	Edge (Chromium & IE Mode), Firefox, Chrome, Safari	No, Yes, No, No, No, No
Exchange Server 2016 OWA Light	Edge, Firefox, Chrome, Safari	S/MIME not available

Supported Email Clients

Version	Clients
Exchange Server SE	Microsoft 365 Apps, Outlook 2024/2021/2019/2016, Outlook for Mac, iOS, Android
Exchange Server 2019	Same as above
Exchange Server 2016	Same as above

.NET Framework Requirements

Version	OS	.NET Framework
Exchange Server SE	Windows Server 2025/2022	.NET Framework 4.8.1 (recommended) or 4.8
Exchange Server 2019 CU15/CU14	Windows Server 2025/2022	.NET Framework 4.8.1 or 4.8
Exchange Server 2019 CU15/CU14	Windows Server 2019	.NET Framework 4.8
Exchange Server 2016 CU23	All supported OS	.NET Framework 4.8

Why Choose Medha Cloud for Exchange Server Support?

With deep expertise in Microsoft technologies, Medha Cloud offers proactive, end-to-end support for Exchange Server environments — from legacy systems to modern hybrid deployments. Our services include:

• Ongoing patching and updates
• Migration planning and execution
• Troubleshooting and high-availability setup
• Version upgrades and deprecation support

Whether you’re dealing with compatibility issues or planning to migrate to Microsoft 365, our team ensures your Exchange deployment is secure, scalable, and fully compliant.

Ready to Upgrade or Migrate?

➡️ Upgrade your Exchange Server with confidence using our managed services.
➡️ Migrate to Microsoft 365 with zero downtime and expert guidance.

For full support from certified Exchange professionals, visit:
Medha Cloud Exchange Server Support